Is Nicotinamide Riboside FDA-approved?

No. It's sold as a dietary supplement, and FDA doesn't approve supplements. Drugs@FDA lists no application with nicotinamide riboside as an active ingredient.

Checked 1 Nov 2026. The sources are below.

Nicotinamide Riboside

Also: NR, nicotinamide riboside chloride, ribosylnicotinamide

Status label in the Peptimes Library
Dietary Supplement
Routes in Peptimes
Oral
Updated
1 Nov 2026

US regulatory status

  • FDA status

    Dietary supplements aren't FDA-approved: FDA does not approve them for safety and effectiveness.

    Source: FDA, checked 1 Nov 2026

  • FDA status

    In 2016 FDA had no questions about a notifier's conclusion that nicotinamide riboside chloride is generally recognized as safe (GRAS) as a source of vitamin B3 in certain foods and drinks (GRN 635). That is not an FDA approval.

    Source: FDA, checked 1 Nov 2026

What studies have looked at

Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.

  • Review of studies

    A 2026 systematic review of 113 studies (33 in people, 80 in rodents) found that in people NR and NMN consistently raised NAD-related markers in blood or cells, but effects on functional, metabolic, vascular and other health outcomes were mixed and often absent.

    Source: PMID 41655607, checked 1 Nov 2026

How to track it in Peptimes

Add nicotinamide riboside in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry is called “NR (Nicotinamide Riboside)” and shows the status label “Dietary Supplement”. It is a separate Library entry from NMN and NAD+.

  • Logging: the amount you took and how you feel. It’s logged as oral, so there’s no injection site to record.
  • Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.

Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell nicotinamide riboside or any other compound.

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