Is MGF FDA-approved?

No. MGF isn't FDA-approved, and Drugs@FDA lists no application with mechano growth factor as an active ingredient.

Checked 1 Nov 2026. The sources are below.

MGF

Also: Mechano Growth Factor, IGF-1Ec peptide, IGF-1 Ec splice variant

Status label in the Peptimes Library
Not FDA-Approved
Routes in Peptimes
Intramuscular
Updated
1 Nov 2026

US regulatory status

  • FDA status

    Not FDA-Approved. Drugs@FDA lists no application with mechano growth factor (MGF) as an active ingredient.

    Source: Drugs@FDA, checked 1 Nov 2026

What studies have looked at

Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.

  • In animals or the lab

    In muscle stem cells from healthy donors, a 24-amino-acid MGF E peptide extended growth life span and delayed senescence in cells from newborn and young-adult muscle, but not in cells from older adults. Lab (cell) data.

    Source: PMID 21354439, checked 1 Nov 2026

  • In animals or the lab

    Scientists at two drug companies could not reproduce the effects claimed for MGF: it did not increase the growth of mouse or human muscle cells or change how they matured, while IGF-1 did. Lab (cell) data.

    Source: PMID 24253050, checked 1 Nov 2026

How to track it in Peptimes

Add MGF in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Not FDA-Approved”.

  • Logging: the amount you took and how you feel.
  • Injection sites: each dose records the site, and Insights shows where you’ve injected and how recently. It never suggests where to inject next.
  • Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.

Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell MGF or any other compound.

More sources

  • FDA, Global Substance Registration System, Mechano growth factor, checked 1 Nov 2026: its sequence of 24 amino acids and the names MGF and IGF-1Ec.

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