Track mecasermin in Peptimes™
Mecasermin is human insulin-like growth factor 1 (IGF-1) made by recombinant DNA technology: a single chain of 70 amino acids, identical to the IGF-1 the body makes. It is the active ingredient in Increlex. (Source: DailyMed label.)
Is mecasermin FDA-approved?
Yes, as a specific product: Increlex (mecasermin) injection is FDA-approved for the use in its label.
Mecasermin
Also: IGF-1, rhIGF-1, recombinant human insulin-like growth factor 1, somatomedin C
- Status label in the Peptimes Library
- FDA Approved
- Routes in Peptimes
- Subcutaneous
- Updated
- 1 Nov 2026
US regulatory status
FDA approval belongs to the product below, for its route and the uses in its label. Label uses are shortened unless quoted.
Increlex (mecasermin) injection
Subcutaneous
Growth failure in children 2 years and older with severe primary IGF-1 deficiency, or with growth hormone gene deletion and neutralizing antibodies to growth hormone. The label says it is not a substitute for growth hormone.
Source: DailyMed label, checked 1 Nov 2026
Investigational
No, for the product and uses above.
Source: Drugs@FDA, checked 1 Nov 2026
What studies have looked at
Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.
- In humans
A registry of 102 children and teenagers with severe primary IGF-1 deficiency who reached near-adult height on Increlex: height gain was greatest in those not treated before, and almost half of those who started before puberty reached the normal adult range; 10.5% of those with Laron syndrome did.
Source: PMID 40626687, checked 1 Nov 2026
How to track it in Peptimes
Add mecasermin in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “FDA Approved”; the entry above gives the detail. Modified forms such as IGF-1 LR3 and IGF-1 DES are different substances and aren’t FDA-approved.
- Logging: the amount you took and how you feel.
- Injection sites: each dose records the site, and Insights shows where you’ve injected and how recently. It never suggests where to inject next.
- Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.
Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell mecasermin or any other compound.
More sources
- FDA, Drugs@FDA, BLA 021839 (Increlex), checked 1 Nov 2026: product, route and marketing status.
- FDA, Global Substance Registration System, Mecasermin, checked 1 Nov 2026: the names insulin-like growth factor I and somatomedin C.
Related pages
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