Track klotho in Peptimes™
Klotho (alpha-klotho) is a protein, not a short peptide. The 1997 study that named it found that a defect in the mouse klotho gene leads to a syndrome resembling ageing; the gene encodes a membrane protein. (Source: PubMed.)
Is klotho FDA-approved?
No. Klotho isn't FDA-approved, and Drugs@FDA lists no application with it as an active ingredient.
Klotho
Also: alpha-klotho, α-klotho, soluble klotho
- Status label in the Peptimes Library
- Not FDA-Approved
- Routes in Peptimes
- SubcutaneousIntramuscularOralSublingualNasalTopicalOther
- Updated
- 1 Nov 2026
US regulatory status
What studies have looked at
Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.
- In animals or the lab
Mice with a defect in klotho gene expression developed a syndrome resembling human ageing, including a short lifespan, infertility, arteriosclerosis, skin atrophy, osteoporosis and emphysema.
Source: PMID 9363890, checked 1 Nov 2026
- In animals or the lab
Mice genetically engineered to overproduce klotho lived longer than normal mice. Klotho acted as a circulating hormone that dampened insulin and IGF-1 signalling. No klotho was given in this study.
Source: PMID 16123266, checked 1 Nov 2026
How to track it in Peptimes
Add klotho in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Not FDA-Approved”.
- Routes: the app lets you record whichever route you used; none is established. Its routes are subcutaneous, intramuscular, oral, sublingual, nasal, topical and Other.
- Logging: the amount you took, the route and how you feel.
- Injection sites: subcutaneous and intramuscular doses record the site, and Insights shows where you’ve injected and how recently. It never suggests where to inject next. Other routes skip this step.
- Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.
Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell klotho or any other compound.
More sources
- FDA, Global Substance Registration System, Klotho secreted peptide, checked 1 Nov 2026: the protein sequence of the secreted form, and the name alpha-klotho.