Track IGF‑1 DES in Peptimes™
IGF-1 DES is human insulin-like growth factor 1 (IGF-1) without its first three amino acids: a protein of 67 amino acids, residues 4 to 70 of IGF-1. (Source: FDA's substance registry (GSRS).)
Is IGF-1 DES FDA-approved?
No. IGF-1 DES isn't FDA-approved, and Drugs@FDA lists no application with it as an active ingredient. It isn't mecasermin (Increlex).
IGF-1 DES
Also: des(1-3)IGF-1, des(1-3)IGF-I, truncated IGF-1
- Status label in the Peptimes Library
- Not FDA-Approved
- Routes in Peptimes
- SubcutaneousIntramuscular
- Updated
- 1 Nov 2026
US regulatory status
What studies have looked at
Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.
- In animals or the lab
Researchers purified a shortened form of IGF-1 from cow colostrum and sequenced it: it lacked the first three amino acids, Gly-Pro-Glu. In rat muscle cells it was about 10 times as active as IGF-1 at stimulating protein synthesis and slowing protein breakdown. Cell data.
Source: PMID 3390164, checked 1 Nov 2026
- In animals or the lab
In marmosets and pigs, IGF-1 variants that bind poorly to IGF-binding proteins lowered blood glucose 2 to 3 times more potently than IGF-1, and for longer; des(1-3)IGF-I was the most potent of those tested. Animal data.
Source: PMID 9415072, checked 1 Nov 2026
How to track it in Peptimes
Add IGF-1 DES in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Not FDA-Approved”.
- Routes: subcutaneous or intramuscular. Choose the one that matches each dose.
- Logging: the amount you took, the route and how you feel.
- Injection sites: subcutaneous and intramuscular doses record the site, and Insights shows where you’ve injected and how recently. It never suggests where to inject next.
- Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.
Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell IGF-1 DES or any other compound.
More sources
- FDA, Global Substance Registration System, Des(1-3) human insulin-like growth factor I, checked 1 Nov 2026: residues 4 to 70 of human IGF-1, and the name des(1-3)IGF-1.
- FDA, Drugs@FDA, BLA 021839 (Increlex, mecasermin), checked 1 Nov 2026: the FDA-approved IGF-1 product, which is a different substance.