Is Collagen Peptides FDA-approved?

No. Collagen peptides are sold as dietary supplements, and FDA doesn't approve supplements. Drugs@FDA lists no collagen peptide drug.

Checked 1 Nov 2026. The sources are below.

Collagen Peptides

Also: hydrolyzed collagen, hydrolysed collagen, collagen hydrolysate, gelatin hydrolysate

Status label in the Peptimes Library
Dietary Supplement
Routes in Peptimes
Oral
Updated
1 Nov 2026

US regulatory status

  • FDA status

    Dietary supplements aren't FDA-approved: FDA does not approve them for safety and effectiveness.

    Source: FDA, checked 1 Nov 2026

  • FDA status

    Drugs@FDA lists no application with collagen peptides or collagen hydrolysate as an active ingredient.

    Source: Drugs@FDA, checked 1 Nov 2026

What studies have looked at

Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.

  • Review of studies

    A 2021 review of 19 randomised, double-blind, controlled trials (1,125 people aged 20 to 70, 95% women) found more improvement in skin hydration, elasticity and wrinkles with hydrolyzed collagen than with placebo.

    Source: PMID 33742704, checked 1 Nov 2026

  • Review of studies

    A 2025 review of 23 randomised trials (1,474 people) found improvements when all trials were pooled, but none in trials without pharmaceutical-company funding or in high-quality trials. The authors found no clinical evidence to support collagen supplements for skin aging.

    Source: PMID 40324552, checked 1 Nov 2026

How to track it in Peptimes

Add collagen peptides in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Dietary Supplement”.

  • Logging: the amount you took and how you feel. It’s logged as oral, so there’s no injection site to record.
  • Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.

Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell collagen peptides or any other compound.

More sources

  • FDA, FDA 101: Dietary Supplements, checked 1 Nov 2026: FDA doesn’t approve dietary supplements for safety and effectiveness.
  • León-López and others, Molecules, 2019, Hydrolyzed Collagen: Sources and Applications, checked 1 Nov 2026: hydrolyzed collagen is a group of low-molecular-weight peptides made by breaking collagen down with enzymes, from bovine, porcine or marine sources.
  • FDA, Global Substance Registration System, Hydrolyzed porcine collagen, checked 1 Nov 2026: one example material, also listed as gelatin hydrolysate.

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