Track apelin in Peptimes™
Apelin is a family of peptides that act on the apelin receptor (APJ). FDA's substance registry lists apelin-13, one of its forms, as a peptide of 13 amino acids and an agonist of the apelin receptor. (Source: FDA's substance registry (GSRS).)
Is apelin FDA-approved?
No. Apelin isn't FDA-approved, and Drugs@FDA lists no application with it as an active ingredient.
Apelin
Also: apelin-13, [Pyr1]-apelin-13, apelin-17, apelin-36
- Status label in the Peptimes Library
- Not FDA-Approved
- Routes in Peptimes
- OtherSubcutaneous
- Updated
- 1 Nov 2026
US regulatory status
What studies have looked at
Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.
- In humans
Randomised, double-blind, placebo-controlled studies in 18 people with chronic heart failure, 6 having coronary angiography and 26 healthy volunteers: apelin widened blood vessels and raised cardiac output, and raised heart rate only in the healthy volunteers.
Source: PMID 20385929, checked 1 Nov 2026
- In humans
A randomised, double-blind, placebo-controlled crossover study in 12 people with chronic kidney disease and 12 matched healthy people: apelin raised kidney blood flow by about 15%. In the kidney-disease group only, filtration rate fell by about 10% and protein in the urine by about 25%.
Source: PMID 39402039, checked 1 Nov 2026
How to track it in Peptimes
Add apelin in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Not FDA-Approved”.
- Routes: Other or subcutaneous. Choose the one that matches each dose.
- Logging: the amount you took, the route and how you feel.
- Injection sites: subcutaneous doses record the site, and Insights shows where you’ve injected and how recently. It never suggests where to inject next. Doses logged as Other skip this step.
- Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.
Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell apelin or any other compound.
More sources
- FDA, Global Substance Registration System, Apelin-13, checked 1 Nov 2026: its sequence of 13 amino acids and its listing as an agonist of the apelin receptor. GSRS also has a record for apelin.
- FDA, Drugs@FDA, checked 1 Nov 2026: no application lists apelin as an active ingredient.