Track AICAR in Peptimes™
AICAR (acadesine) is a nucleoside, 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, with the formula C9H14N4O5. It is not a peptide. (Source: FDA's substance registry (GSRS).)
Is AICAR FDA-approved?
No. AICAR (acadesine) isn't FDA-approved, and Drugs@FDA lists no application with it as an active ingredient.
AICAR
Also: acadesine, AICA riboside, GP-1-110
- Status label in the Peptimes Library
- Not FDA-Approved
- Routes in Peptimes
- Other
- Updated
- 1 Nov 2026
US regulatory status
What studies have looked at
Each point says who or what was studied and what the study reported, with its source and the date we checked it. These are findings from the sources cited, not advice or a promise of any result.
- Review of studies
A pooled analysis of 5 placebo-controlled trials in 4,043 people having bypass surgery: acadesine lowered perioperative heart attacks by 27% and cardiac death to day 4 by 50%; stroke wasn't significantly reduced. A later phase 3 trial, RED-CABG (NCT00872001), was terminated.
Source: PMID 9002496, checked 1 Nov 2026
- In humans
In 10 men with type 2 diabetes, AICAR reduced the liver's glucose output, so blood glucose fell more than with saline; fatty-acid release and levels also fell.
Source: PMID 18709353, checked 1 Nov 2026
How to track it in Peptimes
Add AICAR in My Protocols and set the schedule you already follow: days of the week, times of day and a start date. Peptimes never suggests an amount when you log or schedule a dose. Its Library entry shows the status label “Not FDA-Approved”.
- Route: Other.
- Logging: the amount you took and how you feel. Doses logged as Other have no injection site to record.
- Reminders and history: reminders at your times, Dose History, the Calendar and CSV or JSON export work as described on the peptide tracker app page.
Peptimes is a tracking app, not medical advice. Talk to a licensed clinician about your treatment. Peptimes doesn’t sell AICAR or any other compound.
More sources
- NIH, ClinicalTrials.gov, RED-CABG (NCT00872001), checked 1 Nov 2026: a phase 3 study of acadesine in bypass surgery, terminated after enrolling 3,080 people.
- FDA, Global Substance Registration System, Acadesine, checked 1 Nov 2026: its chemical name, formula and the code name GP-1-110.